Reprogramming Tumour Biology
Duke Street Bio is focused on exploiting tumour genetic vulnerabilities and harnessing the natural power of the body’s immune system to fight cancer.
Next-Gen DDR Therapies
Duke Street Bio is developing the next generation of molecules targeting DNA Damage Repair (DDR) deficiencies in cancer.
Next-Gen IO therapies
At Duke Street Bio we are developing proprietary molecules that convert immune-resistant ‘cold’ tumours to immunotherapy-responsive ‘hot’ tumours. These molecules prime the immune system to relieve the brake applied by cancer and unleash the power of the anti-tumour immune response.

Delivering life-saving cancer treatments to improve patient outcomes.