Scientific Publications and Presentations

Yarza, et al Novel next generation PARP1 selective and CNS penetrant inhibitor DSB2455 – A Phase Ia/Ib Open Label, Multi-Centre Dose Escalation Study with Expansion Cohorts to Assess the Safety, Tolerability, and Activity as Monotherapy in Participants with Advanced Malignancies
– ESMO Conference 2025
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Cowley, et al Profiling of PARP1-selective inhibitor DSB2455 in HR deficient and proficient cancer models as monotherapy and in combination EORTC-NCI-AACR Symposium 2024
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Nelson, et al Investigating PARP1 selective inhibitor DSB1559 efficacy in BRCA1-associated triple negative breast cancer AACR Annual Meeting 2024
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Cowley, et al Characterization of highly selective & CNS-penetrant PARP1 inhibitors AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics 2023
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Cowley, et al Characterization of a novel series of highly selective PARP1 inhibitors AACR Annual Meeting 2023
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Cowley, et al Characterization of a novel series of highly selective PARP7 inhibitors AACR Annual Meeting 2023
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